Keep track of patients for indications of respiratory despair that may be greater than if not predicted and reduce the dosage of DILAUDID INJECTION and/or even the muscle relaxant as needed.

Hydromorphone is thought to get considerably excreted from the kidney, and the chance of adverse reactions to this drug can be bigger in clients with impaired renal operate.

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Explain to your medical doctor When you are pregnant or plan to become Expecting. If you utilize hydromorphone injection on a regular basis for the duration of your pregnancy, your infant may possibly knowledge daily life-threatening withdrawal indications right after start.

Disclaimer: The information offered on this website page will not be a substitute for Qualified health care advice, prognosis, or therapy. Should you have any issues or worries about your wellbeing, you should speak to a health care provider.

Propulsive peristaltic waves inside the colon are lessened, while tone can be increased to The purpose of spasm, leading to constipation. Other opioid-induced outcomes may well consist of a discount in biliary and pancreatic secretions, spasm of sphincter of Oddi, and transient elevations in serum amylase.

Hydromorphone was not mutagenic during the in vitro bacterial reverse mutation assay (Ames assay). Hydromorphone wasn't clastogenic in both the in vitro human lymphocyte chromosome aberration assay or perhaps the in vivo mouse micronucleus assay.

Although the hazard of habit in almost any specific is unfamiliar, it could manifest in patients properly prescribed DILAUDID INJECTION. Addiction can arise at suggested dosages and If your drug is misused or abused.

The concomitant use of opioids with other medications that have an affect on the serotonergic neurotransmitter program has resulted in serotonin syndrome.

Hydromorphone and morphine are narcotics that perform in the same way, so their drug interactions also are related.

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As the duration of opioid reversal is expected for being less than the duration of hydromorphone in DILAUDID INJECTION, meticulously keep track of the patient until spontaneous respiration is reliably reestablished.

Convey to your healthcare company if you're taking any of the next due to the fact these prescription drugs communicate with Viagra® and generic Viagra®:

Observe neonates exposed to opioid analgesics for the duration of labor for signs of extra sedation and respiratory depression.